Pakistani Taliban spokesman Azam Tariq told that the Taliban carried out the attack, which police say targeted building that housed a Crime Investigation Department facility.
Pakistani security forces have been battling the group in the country's tribal region, which borders Afghanistan.
The blast occurred in a high-security area, near government buildings and major hotels, such as the Pearl Continental and the Sheraton. The US consulate is in the general vicinity but was not considered the target.
A Pakistani government official told that about five gunmen on foot cleared the way for the suicide car bomber by firing on security personnel manning a security check post.
Once the vehicle cleared the check post it raced toward the police facility and rammed into the building.
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